Antonios Makrigiannakis


Academic Education and Specialty Training
Professor A. Makrigiannakis was born in Greece in 1964. He graduated from the Medical School of the National and Kapodistrian University of Athens (1988) and completed his PhD in Reproductive Endocrinology and Pharmacology (1994) at the Medical School of the University of Crete. He trained in Obstetrics and Gynecology at the University Hospital of Heraklion, Crete (1993–1997) and was licensed to practice Obstetrics and Gynecology by the Ministry of Health (1997).
Postdoctoral Research and Fellowship Training He was a Postdoctoral Fellow at the University of Pennsylvania, Division of Human Reproduction, Department of Obstetrics and Gynecology, Philadelphia, USA (1997-1999) and a Clinical Fellow at the In Vitro Fertilization Unit, Department of Reproductive Surgery & Medicine, Imperial College School of Medicine, Hammersmith Hospital, London, UK (1999-2001).

Research Activity
He conducts basic and clinical research primarily on the mechanisms of implantation and endometrial receptivity, including reproductive immunology and receptivity markers. His research focuses on the role of CRH in human reproduction and the study of recurrent implantation failures. His main achievement was the description of the mechanism by which trophoblast and decidual CRH immunomodulate the local immunity of maternal T-cells, facilitating implantation. This research resulted in a large volume of publications in scientific journals with a high impact factor (>5), as well as invitations to author scientific reviews in high-impact journals.

Due to the significant impact of his research, he was appointed Assistant Professor at the Department of Obstetrics and Gynecology, Division of Human Reproduction, Philadelphia, USA, and senior scientist at the Imperial College School of Medicine, London, UK (1999-2001). To date, his total scientific activity includes 195 publications with 10,139 citations (Scopus) and an H-index of 50, as well as 8 books and 16 chapters. His wide recognition led to him being a reviewer for more than 15 scientific journals and receiving more than 10 national and international awards. Additionally, he has been an invited speaker at more than 400 international conferences.

Current Academic and Administrative Positions

  • Professor of Obstetrics and Gynecology, Medical School, University of Crete.
  • Director of the Obstetrics and Gynecology Department, University General Hospital of Heraklion.
  • Director of the 1st Surgical Sector, University General Hospital of Heraklion.
  • Certification Committee Coordinator of European Society of Human Reproduction and Embryology (ESHRE)
  • Assessor for the accreditation of subspecialty of training in Reproductive Medicine by the European Society of Human Reproduction and Embryology (ESHRE) and the European Board & College of Obstetrics and Gynaecology (EBCOG).
  • Chairman of the Clinical Awards Committee of the European Society of Human Reproduction and Embryology (ESHRE).
  • Member of the Board of Directors of the Mediterranean Society for Reproductive Medicine (MSRM).
  • Member of the Board of Directors of the Hellenic Obstetrical and Gynecological Society.
    Previous Administrative Positions
  • Vice Dean of the Medical School, University of Crete.
  • Coordinator of the Special Interest Group (SIG) for the Endometrium in the International Society for In Vitro Fertilization (ISIVF).
  • Coordinator for the accreditation of subspecialty training in Reproductive Medicine by the European Society of Human Reproduction and Embryology (ESHRE) and the European Board & College of Obstetrics and Gynaecology (EBCOG).
  • Member of the Advisory Committee of the European Society of Human Reproduction and Embryology (ESHRE)
  • Member of the Board of Directors of the European Society of Human Reproduction and Embryology (ESHRE).
  • Member of the Scientific Committee of the European Board & College of Obstetrics and Gynaecology (EBCOG).
  • President of the Mediterranean Society for Reproductive Medicine (MSRM).
  • General Secretary of the Mediterranean Society for Reproductive Medicine (MSRM).
  • Member of the Board of Directors of the European Society for Clinical Investigation (ESCI)

Grants / Funding

  1. Alexander S. Onassis Foundation (1997-1999).
  2. Wyeth, USA (1999).
  3. Empirikion Foundation (2000).
  4. Alexander S. Onassis Foundation (2002-2004).
  5. IKYDA Program Grant – IKY (State Scholarships Foundation) (2003-2005).
  6. PENED Program (03ΕΔ626, CSF 00098-1) (2003).
  7. Hellenic Obstetrical and Gynecological Society (2004).
  8. Procter & Gamble (2007-2008).
  9. Procter & Gamble (2013-2014).
  10. H.F.R.I. (Hellenic Foundation for Research and Innovation) Program (2021).
  11. Horizon Europe Framework Program (HORIZON) – TULIP (2026 – 2027 )



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Antonios Makrigiannakis